Color-Manage this View is enabled by default and should usually not be changed. When enabled it will interpret the current image according to the color profile attached to it and possibly also depending on the monitor profile if set. When Proof Colors is enabled, that will also influence this view. Note that you can have several views of the same image with different settings to be able to compare the outcome. When this setting is disabled, your image will be interpreted as if it was sRGB.